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GDC-0339 AD hydrochloride(x) InChi: InChI=1S/C10H15BrN5O14P3/c11-9-13-3-6(14-10(12)15-7(3)19)16(9)8-5(18)4(17)2(28-8)1-27-32(23

SKU: 60158940967

4.6
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Description

InChi: InChI=1S/C10H15BrN5O14P3/c11-9-13-3-6(14-10(12)15-7(3)19)16(9)8-5(18)4(17)2(28-8)1-27-32(23

H2O/c1-6-22-19-38(22

PF-4800567 shows inhibitory activity against CK1ϵ and CK1δ in whole cells

SK-Hep-1 cells) induces cell apoptosis

an allosteric heat shock protein 70 (Hsp70) inhibitor

GDC-0339 AD hydrochloride(x) InChi: InChI=1S/C10H15BrN5O14P3/c11-9-13-3-6(14-10(12)15-7(3)19)16(9)8-5(18)4(17)2(28-8)1-27-32(23GDC 0339 is a potent, orally bioavailable and well tolerated pan Pim kinase inhibitor, with Kis of 0. 03 nM, 0. 1 nM and 0. 02 nM for Pim1, Pim2 and Pim3, respectively. GDC 0339 is discovered as a potential treatment of multiple myeloma. Product information CAS Number: 1428569 85 0 Molecular Weight: 465. 50 Formula: C20H22F3N7OS Chemical Name: 5 amino N {5 [(4R,5R) 4 amino 5 fluoroazepan 1 yl] 1 methyl 1H pyrazol 4 yl} 2 (2,6 difluorophenyl) 1,3

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