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CC-90003 ader-1 C2HF3O2/c46-45(47)49-24-9-18-34-40(57)48-23-10-19-35(51-39(56)22-21-29-12-3-1-4-13-29)44(61)55-25-11-20-38(55)43(60)54-36(26-30-14-5-2-6-15-30)41(58)53-37(42(59)52-34)27-31-28-50-33-17-8-7-16-32(31)33

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Description

C2HF3O2/c46-45(47)49-24-9-18-34-40(57)48-23-10-19-35(51-39(56)22-21-29-12-3-1-4-13-29)44(61)55-25-11-20-38(55)43(60)54-36(26-30-14-5-2-6-15-30)41(58)53-37(42(59)52-34)27-31-28-50-33-17-8-7-16-32(31)33

Chemically Induced Degradation of Anaplastic Lymphoma Kinase (ALK)

424(1):47-60

Sahebkar A

2-diyl ditetradecanoate is an endogenous metabolite

CC-90003 ader-1 C2HF3O2/c46-45(47)49-24-9-18-34-40(57)48-23-10-19-35(51-39(56)22-21-29-12-3-1-4-13-29)44(61)55-25-11-20-38(55)43(60)54-36(26-30-14-5-2-6-15-30)41(58)53-37(42(59)52-34)27-31-28-50-33-17-8-7-16-32(31)33CC 90003 is an irreversible and selective inhibitor of ERK 1 2 with antitumor activity. Product information CAS Number: 1621999 82 3 Molecular Weight: 458. 44 Formula: C22H21F3N6O2 Chemical Name: N [2 ({2 [(2 methoxy 5 methylpyridin 4 yl)amino] 5 (trifluoromethyl)pyrimidin 4 yl}amino) 5 methylphenyl]prop 2 enamide Smiles: COC1C=C(NC2N=C(NC3=CC=C(C)C=C3NC(=O)C=C)C(=CN=2)C(F)(F)F)C(C)=CN=1 InChiKey: ILUKRINUNLAVMH UHFFFAOYSA N InChi: InChI=1S

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